Therapeutic targeting of STAT pathways in CNS autoimmune diseases
نویسندگان
چکیده
منابع مشابه
Therapeutic targeting of STAT pathways in CNS autoimmune diseases
Signal transducers and activators of transcription (STATs) transduce extracellular signals that regulate the initiation, duration and intensity of immune responses. However, unbridled activation of STATs by pro-inflammatory cytokines or growth factors contributes to pathogenic autoimmunity. In this review, we briefly discuss STAT pathways that promote the development and expansion of T cells th...
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ژورنال
عنوان ژورنال: JAK-STAT
سال: 2013
ISSN: 2162-3996
DOI: 10.4161/jkst.24134